1-METHYL-5-NITRO-ISATIN
Preparation- Product Name
- 1-METHYL-5-NITRO-ISATIN
- CAS No.
- 3484-32-0
- Chemical Name
- 1-METHYL-5-NITRO-ISATIN
- Synonyms
- 1-METHYL-5-NITRO-ISATIN;1-METHYL-5-NITROINDOLINE-2,3-DIONE;1H-Indole-2,3-dione, 1-methyl-5-nitro-
- CBNumber
- CB5431395
- Molecular Formula
- C9H6N2O4
- Formula Weight
- 206.15
- MOL File
- 3484-32-0.mol
1-METHYL-5-NITRO-ISATIN Property
- storage temp.
- Sealed in dry,Room Temperature
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 3484320
- Product name
- 1-Methyl-5-nitroindoline-2,3-dione
- Packaging
- 1g
- Price
- $386.9
- Updated
- 2021/12/16
- Product number
- CM242343
- Product name
- 1-Methyl-5-nitroindoline-2,3-dione
- Purity
- 95%
- Packaging
- 1g
- Price
- $422
- Updated
- 2021/12/16
- Product number
- CD11138706
- Product name
- 1-Methyl-5-nitroindoline-2,3-dione
- Purity
- 95+%
- Packaging
- 1g
- Price
- $447
- Updated
- 2021/12/16
1-METHYL-5-NITRO-ISATIN Chemical Properties,Usage,Production
Preparation
A mixture of nitroisatin 31 (10 g, 0.052 mol), MeI (16.21 ml, 0.260 mol) and K2CO3 (21.56 g, 1.56 mol) in anhydrous DMF was stirred overnight at room temperature. Water was added to the reaction mixture and acidified with dilute HCl till acidic to pH paper. A yellow solid separated, 1-Methyl-5-nitroisatin was filtered and washed thoroughly with water till neutral to pH paper and air dried to a constant weight (9.66 g).
Synthesis Reference(s)
Journal of Medicinal Chemistry, 39, p. 5072, 1996 DOI: 10.1021/jm960603e